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2026
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Jan 2026
In vitro and in vivo efficacy of epithelial barrier promoting barriolides as potential therapy for ulcerative colitis
Joelsson JP, Parnham MJ, Froment L, Rapet A, Hugi A, Stucki J, Hobi N, Kricker JA
biomedicines
Article
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Nov 2025
The effects of a novel macrolide glasmacinal (EP395) on alveolar macrophage phenotype and phagocytosis in COPD
Lea S, Li J, Baker J, Kricker J, Parnham MJ, Singh D
Eur Resp J
Conference Abstract
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Nov 2025
EP395, a novel non-antibiotic macrolide, enhances antiviral responses in bronchial epithelial cells from asthma patients
Malm Tillgren S, Menzel M, Kricker J, Parnham MJ, Norris V, Bech M, Uller L
BTS Winter Meeting
Conference Abstract
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Oct 2025
Promoting Immune Defensive Responses of Epithelial Cells in Airway Disease
Parnham MJ, Norris V, Kricker JA
Frontiers in Allergy
Review
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Sep 2025
Effects of EP395, a novel macrolide, on acute neutrophilic airway inflammation
Kricker JA, Norris V, Page CP, Parnham MJ
Pulm Pharmacol Ther.
Article
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Sep 2025
A novel macrolide, EP395, with reduced antibacterial activity and an enhancing effect on respiratory epithelial barrier.
Gudjonsson T, Joelsson JP, Arason AJ, Asbjarnarson A, Gardarsson FR, Lehmann F, Teodorovic P, Ingthorsson, Sigurdsson S, Valdimarsdottir B, Parnham MJ, Page C, Kricker JA
Pulm Pharmacol Ther.
Article
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Mar 2025
The Non-Antibacterial Effects of Azithromycin and Other Macrolides on the Bronchial Epithelial Barrier and Cellular Differentiation
Asbjarnarson A, Joelsson JP, Gardarsson FR, Sigurdsson S, Parnham MJ, Kricker JA, Gudjonsson T
Eur Resp J
Article
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Oct 2024
The new macrolide EP395 reduces airway eosinophilic inflammation
Kricker JA, Norris V, Page CP, Riffo-Vasquez Y, Parnham MJ.
Eur Resp J
Conference Abstract
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Jan 2024
Macrolides and diseases associated with loss of epithelial barrier integrity
Page CP, Gardarsson FR, Kricker JA, Gudjonsson T, Norris V, Parnham MJ
Progress in inflammation research
Book Chapter
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